Alzheimer’s study finds one protein may hold key to brain’s cleanup system

Scientists have identified a potential new strategy for slowing Alzheimer’s disease after finding that blocking a single protein, PTP1B, improved learning and memory in a mouse model of the condition. The study, led by Cold Spring Harbor Laboratory Professor Nicholas Tonks, focuses on how inhibiting PTP1B may help restore the function of microglia, the brain’s immune cells, allowing them to clear amyloid beta plaques more effectively.

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